12th Annual North Eastern Structure Symposium

Storrs, Connecticut
Saturday, October 10, 2015


8:30 AM - 9:00 AM

9:00 AM - 9:15 AM
  Registration and coffee

Welcoming Remarks: Philip Yeagle

9:15 AM - 10:00 AM         Plenary Talk 1 - Introduction: Jim Cole
Rohit Pappu (Washington University at St. Louis)
Sequence-conformation-function relationships of intrinsically disordered proteins

10:00 AM - 10:30 AM        
10:30 AM - 11:00 AM         
  Session 1 - Multiscale Modeling of IDPs
Session chair: Jose Gascon
Jianhan Chen (Kansas State University)
Multi-scale modeling of IDP structure and interaction
Eric May (UConn)
Dynamics of Viral Lytic Peptides in Aqueous and Membrane Environments

11:00 AM - 11:15 AM

11:15 AM - 11:30 AM

11:30 AM - 11:45 AM
  Session 2 - Promoted poster talks
Session Chair: Nathan Alder
Scott Showalter (Penn State)
Structural Biophysics of Intrinsically Denatured Proteins
Nicolas Fawzi (Brown)
Atomic details of FUS granules that bind the C-terminal domain of RNA polymerase II
Chunyu Wang (Rensselaer Polytechnic Institute)
Characterization of AB monomers with multiple fields and high Pressure NMR

11:45 AM - 1:30 PM
  Lunch & Poster Viewing

1:30 PM - 2:00 PM                            
2:00 PM - 2:30 PM  
  Session 3 - Advanced NMR Techniques to Study IDPs
Session chair: Andrei Alexandrescu
Wolfgang Peti (Brown)
IDPs and Protein Phosphatase Regulation: they belong together

Richard Kriwacki (St Jude Children's Research Hospital)
Diverse Roles of Disorder in Protein Function; From Signaling to Organelle Organization

2:30 PM - 3:00 PM

3:00 PM  3:30 PM
  Session 4 - IDPs in molecular assemblies
Session chair: Vikki Robinson
Jean Baum (Rutgers)
The role of intrinsically disordered proteins in aggregation associated with Parkinson’s disease

Ed O’Brien (Penn State)
Accurate prediction of co-translational folding in living cells and the physical origins of critical codon positions

3:30 PM - 4:00 PM   
  Coffee break  

 4:00 PM - 4:45 PM   Plenary Talk 2 - Introduction: Jeff Hoch
Jane Dyson (The Scripps Research Institute)
Disorder and partial order in protein function

 4:45 PM - 5:00 PM  
  Concluding remarks  


Contact Information

  • For programmatic questions, please contact:
    Andrei Alexandrescu
    Department of Molecular and
     Cell Biology
    Phone: 860-486-4414
    Fax: 860-486-4331
    Email: Andrei.alexandrescu@uconn.edu

    For registration questions, please contact:
    University of Connecticut
    University Events and
    Conference Services
    Phone: 860-486-1038
    Email: conferences@uconn.edu
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