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3rd Science Exchange Seminar
Immunogenicity and Tolerance Seminar
Thursday, November 09, 2017 9:30 AM
(Central European Time)
EpiVax is organizing their 3rd seminar on Immunogenicity and Tolerance on November 9th, 2017 in Amsterdam.
This meeting will focus on the determinants of immunogenicity – a key feature of effective vaccines and a key barrier to success in the clinic for protein therapeutics. Conversely, tolerance induction is a key feature of successful protein therapeutics, while suppressing immune responses to vaccines. The reduction of T cell epitopes and introduction of Treg epitopes (like Tregitopes) for protein therapeutics, and the reverse process for vaccines, will be discussed and illustrated in case studies.
Below is the tentative list of speakers and discussion topics:
Annie De Groot, MD
In Vitro Studies Using Human Donor T cells: CD4 T-cell responses against the therapeutic antibody adalimumab in Rheumatoid Arthritis patients
Marieke van Ham, PhD
Immunogenicity of Protein Aggregates and Subvisible Particles
Wim Jiskoot, PhD
Leiden University Medical Center
Circulating Innate Lymphoid Cells are Differentially Regulated in Allergic and Non-allergic Subjects
Vincent Lombardi, PhD
Ab Osterhaus, PhD
University of Veterinary Medicine in Hannover, Germany
Effector, Regulatory and Cytoxic T-cells in Atherosclerosis; Rational Basis for Vaccination
Bram Slütter, PhD
Circulating Normal Immunoglobulins as Regulators of Th17 Responses: What have we learned from monomeric IgA and therapeutic intravenous immunoglobulin IgG?
Institut National de la Santé et de la Recherche Médicale (INSERM) Unité
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